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Broad-Spectrum Digestive Support*

EnzymeMD® works quickly to help reduce discomfort from indigestion, gas, and bloating, particularly after eating. A combination of 18 highly potent, plant-based digestive enzymes and a powerful probiotic, EnzymeMD® helps take digestive worry out of your meals while restoring long-term digestive health.*

  • Developed by a Board-Certified Gastroenterologist
  • Fast-Acting Help to Reduce Indigestion, Gas, and Bloating After Eating*
  • 18 Digestive Enzymes Naturally Aid Breakdown of Crucial Nutrients*
  • With S. boulardii Probiotic to Help Eliminate Toxins and Gases*

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  • Peanut-free
  • Shellfish-Free
  • Non-GMO
  • 90 Day Money Back Guarantee
  • Made in the USA
  • GMP - Good manufacturing process
EnzymeMD® is doctor formulated to help with indigestion, bloating, and restoring long-term digestive health.*
  • Peanut-free
  • Shellfish-Free
  • Non-GMO

Enjoy Your Food Without the Worry

EnzymeMD® helps ensure your body doesn’t have to work overtime to convert hard-to-digest food into the necessary fuel it needs to operate at peak excellence.*

Give Your Body the Enzymes It Needs

  • EnzymeMD® is vegetarian, gluten-free, dairy-free, and 100% non-GMO with no hidden additives, artificial ingredients, or synthetic fillers
  • 18 potent, plant-based digestive enzymes stimulate digestive function and neutralize gas production*
  • Enzymes and an essential probiotic work together to aid digestion and improve gut health*
  • Doctor-formulated ingredients mean an effectiveness you can rely on*
  • Fast-acting enzymes encourage better digestion today and work to improve long-term digestive health as well*

Feel Good Again About What You Eat, Not Worried

EnzymeMD® works fast, but you can enjoy even more benefits when you stick with it over time.

  • After Your First Meal

    Some of the enzymes in EnzymeMD® have been found to significantly reduce gas, bloating, discomfort, and diarrhea, even after patients enjoyed a meal made entirely of cooked beans.*

  • 1 Month

    While the more immediate symptoms of indigestion can be reduced from the start, other benefits to your digestive health take more time to develop.

  • 2 Month

    As you continue taking EnzymeMD®, you will begin to notice the benefits of the S. boulardii probiotic. By helping reinforce the barrier keeping toxins from escaping your gut into the bloodstream.*

  • 3 Month

    As your body continues to become better equipped with the enzymes needed to absorb all the nutrients in your food, you can enjoy the benefits of a healthy diet as well.*

*Individual results may vary. This timeline may not reflect the typical purchaser's experience, and is not intended to represent or guarantee that anyone will achieve the same or similar results.

Doctor Formulated

Dr. David Kahana, MD

Digestive enzymes help breakdown our food. Many GI conditions, such as irritable bowel syndrome, gluten sensitivity, lactose intolerance, bloating, and even reflux and dyspepsia, among others, are caused by poor digestion of food. When food is poorly digested, it is fermented by bacteria, which produce noxious by-products that can cause symptoms, from abdominal pain and diarrhea, to fatigue and cloudy mentation.

Digestive enzymes simply aid the process of digestion, thereby limiting bacterial fermentation. With our food supply becoming increasingly difficult to digest, supplementing with digestive enzymes is an easy and effective way to enhance digestion

1MD's EnzymeMD® incorporates the most important enzymes, which are vegan and derived from yeast, in the highest potency possible. My formulation is designed to help you digest all fats and triglycerides, proteins and peptides, carbs and sugars, and reduce the osmotic load within the lumen, something that can lead to dysmotility and cramping.

The addition of Saccharomyces boulardii, a probiotic yeast, helps eliminate toxins and gases, and also stimulates production of endogenous enzymes, thereby aiding innate digestion.

A Special Formula for Your Digestive Health

Don't just love your food, love how you feel after eating it too

You can rest assured knowing there are never any harmful fillers or additives

View Ingredients

EnzymeMD® Supplement Facts

Serving Size: 2 Capsules | Servings Per Container: 30

  Amount Per Serving %DV

EnzymeMD® Proprietary Blend

Saccharomyces boulardii





Protease (pH 2-3)

Protease (pH 3-6)

Protease (pH 6-9)












420 mg **
  • ** Daily Value Not Established
  • Other Ingredients: Rice Flour, Vegetable Cellulose Capsule
  • * These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
  • Peanut-free
  • Shellfish-Free
  • Non-GMO

How to Take EnzymeMD®

As a dietary supplement, adults take one (1) or two (2) capsules 20 minutes before a meal or as recommended by a healthcare professional.

Customers Speak

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What are people saying?

These upset my system horribly. Bad cramps and terrible diarrhea. I only took them for a couple of days and was disappointed...

This product worked wonders on my gut! I had my gallbladder removed earlier this year but had issues with certain foods that I didn’t have previously. Still don’t regret the surgery but my stomach was in bad shape. This product helped with those issues and I feel so completely normal now, no more food problems!

My husband and I have been using these products for years now and we love them.

This is a wonderful product. We have tried several different brands. 1MD is far and away the best!

Love it!

I was having multiple digestion issues such as belching, stomach gurgling and my stomach always just felt unsettled after eating. I noticed I was not digesting my food and have heard about digestive enzymes and saw 1MD Enzyme MD product on line as rated very highly. I decided to give them a try, and have only been taking for a short time but have noticed already a dramatic difference with less belching and stomach upset within the first week. I know as I continue to take this I will continue to feel even better. I am so thankful for finding this product and would highly recommend to anyone having digestive issues.

I ordered this for my sister and she says that it really works. She says she doesn't remember the last time she was going regular.

These have worked great!

This EnzymeMD is the second of 3 supplements that have helped me with weight loss!

Not good, I bought these to help with digestion since I have no gallbladder. These are causing me a lot of gastric upset along with a lot of belching. I stopped taking them and my symptoms went away.

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What are digestive enzymes?

Digestive enzymes are specialized proteins made by cells in our bodies which help break down foods into usable nutrients that are then absorbed into the digestive tract and distributed throughout the body.

How do enzymes work?

Enzymes work as a catalyst for biochemical reactions, increasing or accelerating the rate of a reaction. These thousands of chemical reactions that occur in our body every second could not happen without enzymes which speed up these reactions without being destroyed or changed in the process. When you increase the amount of enzymes performing these tasks, you decrease the time required for completing the process.

Why do I need to take a digestive enzyme supplement when my food already contains natural enzymes?

It is true that digestive enzymes are produced naturally by the body and are also found in raw, unprocessed foods. However, when we move away from a mostly raw diet, toward a diet comprised of highly processed foods, the amount of digestive enzymes in our bodies dramatically decreases, making it more difficult for us to effectively breakdown food and absorb its nutrients. Placing this extra work on our digestive system can cause side effects like occasional gas, bloating, and indigestion. To help to prevent or reduce these discomforts and assist the body with proper function, a supplemental digestive enzyme is recommended.*

Are there any negative side effects from taking enzymes?

Generally speaking, digestive enzymes effects on the body are positive, helping provide relief from digestive discomforts like gas, bloating, and indigestion. Consult a doctor before you embark on any new health regimen, and as with any dietary supplement, discontinue use immediately if you experience any negative side effects. If you require additional support or have questions, please contact our customer service department. We’re here to help.*

Can I take EnzymeMD® with my other supplements?

Yes, digestive enzymes are frequently taken in combination with various other digestive support supplements including probiotics, fiber supplements, and multivitamins.

Should EnzymeMD® be refrigerated?

No, it is not necessary to refrigerate EnzymeMD® enzymes. We suggest that they be kept in a cool, dry place with a stable temperature at or about 77° F (25°C) or below.

Should EnzymeMD® be taken before, during, or after a meal?

The best time to take EnzymeMD® is 20 - 30 minutes before each meal, or with the first few bites of the meal. If you forget, taking the enzymes at the end of the meal will still provide benefits, as our food stays in the stomach for up to 90 minutes after mealtime.

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