Enjoy free shipping today! Enter code SHIP1MD at checkout.


Broad-Spectrum Digestive Support*

EnzymeMD® works quickly to help reduce discomfort from indigestion, gas, and bloating, particularly after eating. A combination of 18 highly potent, plant-based digestive enzymes and a powerful probiotic, EnzymeMD® helps take digestive worry out of your meals while restoring long-term digestive health.*

  • Developed by a Board-Certified Gastroenterologist
  • Fast-Acting Help to Reduce Indigestion, Gas, and Bloating After Eating*
  • 18 Digestive Enzymes Naturally Aid Breakdown of Crucial Nutrients*
  • With S. boulardii Probiotic to Help Eliminate Toxins and Gases*

Subscribe & Save (UP TO 40% Off)

One-Time Purchase

Automatic Delivery

+ Free Shipping

  • 6 Bottles

    every 6 months




    You Save $102

    Add to cart

    Total $155.94

  • 3 Bottles

    every 3 months




    You Save $39

    Add to cart

    Total $89.97

  • 1 Bottle

    every month




    You Save $7

    Add to cart

    Total $35.99

  • 6 Bottles 23 % Off Best

    $32 99 each
    $42.99 MSRP

    You Save $60.00

    + Free Shipping

    Add to cart Total: 197.94
  • 3 Bottles 14 % Off Best

    $36 99 each
    $42.99 MSRP

    You Save $18.00

    + Free Shipping

    Add to cart Total: 110.97
  • MSRP

    1 Bottle

    $42 99 each
    Add to cart Total: 42.99
  • 90 Day Money Back Guarantee
  • Made in the USA
  • GMP - Good manufacturing process
EnzymeMD® is doctor formulated to help with indigestion, bloating, and restoring long-term digestive health.*
  • Gluten-Free
  • Non-GMO
  • Vegan

Enjoy Your Food Without the Worry

EnzymeMD® helps ensure your body doesn’t have to work overtime to convert hard-to-digest food into the necessary fuel it needs to operate at peak excellence.*

Give Your Body the Enzymes It Needs

  • EnzymeMD® is vegetarian, gluten-free, dairy-free, and 100% non-GMO with no hidden additives, artificial ingredients, or synthetic fillers
  • 18 potent, plant-based digestive enzymes stimulate digestive function and neutralize gas production*
  • Enzymes and an essential probiotic work together to aid digestion and improve gut health*
  • Doctor-formulated ingredients mean an effectiveness you can rely on*
  • Fast-acting enzymes encourage better digestion today and work to improve long-term digestive health as well*

Feel Good Again About What You Eat, Not Worried

EnzymeMD® works fast, but you can enjoy even more benefits when you stick with it over time.

  • After Your First Meal

    Some of the enzymes in EnzymeMD® have been found to significantly reduce gas, bloating, discomfort, and diarrhea, even after patients enjoyed a meal made entirely of cooked beans.*

  • 1 Month

    While the more immediate symptoms of indigestion can be reduced from the start, other benefits to your digestive health take more time to develop.

  • 2 Month

    As you continue taking EnzymeMD®, you will begin to notice the benefits of the S. boulardii probiotic. By helping reinforce the barrier keeping toxins from escaping your gut into the bloodstream.*

  • 3 Month

    As your body continues to become better equipped with the enzymes needed to absorb all the nutrients in your food, you can enjoy the benefits of a healthy diet as well.*

*Individual results may vary. This timeline may not reflect the typical purchaser's experience, and is not intended to represent or guarantee that anyone will achieve the same or similar results.

Doctor Formulated

Dr. David Kahana, MD

Digestive enzymes help breakdown our food. Many GI conditions, such as irritable bowel syndrome, gluten sensitivity, lactose intolerance, bloating, and even reflux and dyspepsia, among others, are caused by poor digestion of food. When food is poorly digested, it is fermented by bacteria, which produce noxious by-products that can cause symptoms, from abdominal pain and diarrhea, to fatigue and cloudy mentation.

Digestive enzymes simply aid the process of digestion, thereby limiting bacterial fermentation. With our food supply becoming increasingly difficult to digest, supplementing with digestive enzymes is an easy and effective way to enhance digestion

1MD's EnzymeMD® incorporates the most important enzymes, which are vegan and derived from yeast, in the highest potency possible. My formulation is designed to help you digest all fats and triglycerides, proteins and peptides, carbs and sugars, and reduce the osmotic load within the lumen, something that can lead to dysmotility and cramping.

The addition of Saccharomyces boulardii, a probiotic yeast, helps eliminate toxins and gases, and also stimulates production of endogenous enzymes, thereby aiding innate digestion.

A Special Formula for Your Digestive Health

Don't just love your food, love how you feel after eating it too

You can rest assured knowing there are never any harmful fillers or additives

View Ingredients

EnzymeMD® Supplement Facts

Serving Size: 2 Capsules | Servings Per Container: 30

  Amount Per Serving %DV

EnzymeMD® Proprietary Blend

Saccharomyces boulardii





Protease (pH 2-3)

Protease (pH 3-6)

Protease (pH 6-9)












420 mg **
  • ** Daily Value Not Established
  • Other Ingredients: Rice Flour, Vegetable Cellulose Capsule
  • * These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
  • Gluten-Free
  • Non-GMO
  • Vegan

How to Take EnzymeMD®

As a dietary supplement, adults take one (1) or two (2) capsules 20 minutes before a meal or as recommended by a healthcare professional.

Customers Speak

Write a Review

What are people saying?

Has made me feel great. I take it with each meal and my gut feels better than ever.

Great product

Just started using, hoping this will work well with the probiotic platinum which has been great so far.

I use this product 15 min before eating a meal and It works every time to help digest my food. Thank you 1MD

The first few days after taking these enzymes my bloating and gas completely went away its amazing I'm going to buy every month

I have had great luck with prebiotics and probiotics, so am looking forward to trying this.

Amazing products at first I didn’t know if I was making the right decision on buying products from here but now I was glad that I did thank you 1md

Great Enzyme! No more acid reflux and indigestion if i over eat or drink coffee or have sweets after dinner.

Very good product

I read the review on this product & although I was taking Complete Probiotics Platinum, I wanted to try it to make sure I had done everything possible to help my body stay healthy, It's a very good product.

They really do work.

I have many digestive issues. 1md Products such as Complete Probiotics, Digesive Enzymes, & Balance MD are the only products that help manage these painful issues. I am grateful for these products, they really do work. If you are thinking of trying any of there products, I urge you to do it. They really do work.

Write a Review

What are digestive enzymes?

Digestive enzymes are specialized proteins made by cells in our bodies which help break down foods into usable nutrients that are then absorbed into the digestive tract and distributed throughout the body.

How do enzymes work?

Enzymes work as a catalyst for biochemical reactions, increasing or accelerating the rate of a reaction. These thousands of chemical reactions that occur in our body every second could not happen without enzymes which speed up these reactions without being destroyed or changed in the process. When you increase the amount of enzymes performing these tasks, you decrease the time required for completing the process.

Why do I need to take a digestive enzyme supplement when my food already contains natural enzymes?

It is true that digestive enzymes are produced naturally by the body and are also found in raw, unprocessed foods. However, when we move away from a mostly raw diet, toward a diet comprised of highly processed foods, the amount of digestive enzymes in our bodies dramatically decreases, making it more difficult for us to effectively breakdown food and absorb its nutrients. Placing this extra work on our digestive system can cause side effects like occasional gas, bloating, and indigestion. To help to prevent or reduce these discomforts and assist the body with proper function, a supplemental digestive enzyme is recommended.*

Are there any negative side effects from taking enzymes?

Generally speaking, digestive enzymes effects on the body are positive, helping provide relief from digestive discomforts like gas, bloating, and indigestion. Consult a doctor before you embark on any new health regimen, and as with any dietary supplement, discontinue use immediately if you experience any negative side effects. If you require additional support or have questions, please contact our customer service department. We’re here to help.*

Can I take EnzymeMD® with my other supplements?

Yes, digestive enzymes are frequently taken in combination with various other digestive support supplements including probiotics, fiber supplements, and multivitamins.

Should EnzymeMD® be refrigerated?

No, it is not necessary to refrigerate EnzymeMD® enzymes. We suggest that they be kept in a cool, dry place with a stable temperature at or about 77° F (25°C) or below.

Should EnzymeMD® be taken before, during, or after a meal?

The best time to take EnzymeMD® is 20 - 30 minutes before each meal, or with the first few bites of the meal. If you forget, taking the enzymes at the end of the meal will still provide benefits, as our food stays in the stomach for up to 90 minutes after mealtime.

Call Now

Write a review

Thank you for your reviewing our product!


Woohoo! You just got up to

33% Off

Claim Your Discount



  • 6 Bottles 33 % Off Best

    $28 99 each
    $42.99 MSRP

    You Save $84.00

    + Free Shipping

    Add to cart Total: $173.94
  • 3 Bottles 23 % Off Best

    $32 99 each
    $42.99 MSRP

    You Save $30.00

    + Free Shipping

    Add to cart Total: $98.97
  • 1 Bottle 9 % Off

    $38 99 each
    $42.99 MSRP

    You Save $4.00

    Add to cart Total: $38.99